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How to Get Stains Out of Kids' Clothes: A Stain-by-Stain Guide for Cotton

Tips
Amanjot Kaur
Amanjot Kaur
16 min read • Nov 10, 2026

To get a stain out of kids' cotton clothes, scrape or blot off what you can, rinse the back of the stain with cold water, rub in liquid detergent or an enzyme stain remover, then wash. Let the piece air dry and check it before it goes near the dryer, because dryer heat can set a stain that is still there.

That sequence handles most of what a two- to six-year-old brings home: grass, tomato sauce, berries, chocolate, milk and potty accidents. A few stains need something different, such as mud, grease, crayon, gum, sunscreen and pen. This guide sorts them by what works, using laundry guides from university extension services and the American Cleaning Institute, and says where those guides disagree. It is written for cotton, which is what our clothes for ages 2 to 6 are made of: 100% combed organic cotton, made by GOTS-certified manufacturers, in a lot of cream, white and pale yellow.

Key takeaways

  • Act early. Iowa State University Extension says fresh stains are much easier to remove than stains more than 24 hours old.
  • Cold water first for protein stains. Milk, egg, blood and potty accidents can set in hot water; start them cold.
  • No dryer until the stain is gone. The American Cleaning Institute and Texas A&M AgriLife both warn that dryer heat can make a stain permanent.
  • Enzymes for food and body stains. A soak of at least 30 minutes in an enzyme product, or several hours for an old stain, is the cleaning institute's advice.
  • Keep chlorine bleach for white cotton, and only if the care label allows it. Never mix it with ammonia or vinegar.
  • Some stains don't come out. Dried paint, permanent marker and some inks can be permanent, so test before you spend an evening on them.
The numbers to know
Four rules that decide most stains

Each comes from the extension or cleaning guide named under it, read on November 10, 2026.

Timing
24 h

Fresh stains are much easier to remove than stains more than 24 hours old.

Iowa State University Extension, AnswerLine

Enzyme soak
30 min

A soak in an enzyme product for at least 30 minutes, or several hours for an old stain.

American Cleaning Institute, 2026

Spot test
2–5 min

How long to leave a stain remover on a hidden seam before you rinse and check the colour.

Mississippi State University Extension, Pub. 1400

Protein stains
Cold

Start milk, egg, blood and potty accidents in cold water; hot water first can cook the protein into the fabric.

University of Kentucky Extension, 1996

Sources are listed at the end of the article.

Child in cream organic cotton pants and a pale yellow shirt leaning on a wall
Knees and grass

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What is the best way to get stains out of kids' clothes?

Work out what kind of stain it is, then treat it before it dries and before it sees heat. The extension guides group stains by what they are made of, because that decides the method. Protein stains such as milk, egg, blood, vomit and potty accidents need cold water and enzymes. Tannin stains such as juice and berries respond to detergent and warmer water. Oily stains such as butter and sunscreen need detergent worked in, or a solvent. Wax and gum come off once they are cold and hard.

The steps below work for most food and body stains on washable cotton:

  1. Lift off what you can. Scrape solids with a dull knife or spoon. Blot liquids with a paper towel; rubbing spreads the stain.
  2. Rinse from the back. Hold the stain face down under cold running water so the water pushes it out of the fabric, not deeper in. The American Cleaning Institute gives this advice for tomato stains.
  3. Pretreat. Rub in liquid laundry detergent or a stain remover. For food and body stains, use a product that contains enzymes and leave it for at least 30 minutes.
  4. Wash. Use the warmest water the care label allows, except for protein stains, which should stay cool until they are gone.
  5. Air dry and check. If any mark is left, treat it again. Iowa State University Extension's advice for sunscreen stains is the same: launder, air dry, check, and repeat if needed.

Test first on anything with a print, embroidery or a strong colour. New Mexico State University's guide says to always test a removal method on an inside seam or hem, and Mississippi State's says to leave it there for two to five minutes before you rinse and look. Embroidery thread can be dyed differently from the fabric under it, so test the thread too.

Stain-by-stain: what to do with the stains kids make

Find the stain, do the first step straight away, and keep the piece out of the dryer until it is gone. The table covers the stains children aged 2 to 6 make most, on washable cotton.

Kids' stains on cotton: first step, then what

Stain First step Then Avoid
Grass Pretreat with an enzyme stain remover Wash in the warmest water the label allows Rubbing it in dry
Mud Let it dry, then brush off as much as you can Soak in detergent and water for at least 30 minutes, then wash Wiping it while wet
Tomato sauce, ketchup Rinse cold water through the back of the stain Rub in liquid detergent, then wash Hot water and the dryer before it is gone
Berries, juice Rinse in cold water Wash with detergent; fabric-safe bleach if a mark is left Leaving it to dry overnight
Chocolate Scrape off the excess Soak in cool water, pretreat, then wash Hot water first
Milk, egg, formula Rinse in cold water Enzyme pretreat or soak, then wash Hot water, which sets protein
Potty accidents, vomit Rinse in cold water Enzyme pretreat or soak, then wash Hot water first; mixing chlorine bleach with ammonia
Blood Soak in cold water Enzyme product in warm water for a dried stain, then wash Hot water
Butter, grease Blot, then work in liquid detergent Wash in the warmest water the label allows The dryer before it is gone
Sunscreen Blot, then massage in liquid detergent or dish soap Wash, air dry, check Soaking and bleach (Iowa State)
Crayon Scrape off what you can Pre-wash stain remover with the stain face down on paper towels, then wash The dryer: heat melts wax
Gum Harden it with ice Crack or scrape it off, then pretreat what is left Pulling it while soft
Water-based paint Rinse in warm water while still wet Pretreat and wash Letting it dry
Pen, permanent marker Test rubbing alcohol on a hidden spot Sponge from the back, then wash Expecting it to come out

Two rows in that table are worth the most. Milk, egg, blood and potty accidents are protein stains: the University of Kentucky's guide says hot water first cooks the protein into the fabric, and Iowa State says the same. And nearly every guide we read warns about the dryer. Texas A&M AgriLife puts it bluntly: never dry a stained piece in the dryer, or it may become impossible to remove.

Grass and mud: the knees of every pair of pants

Grass needs an enzyme pretreatment; mud needs to dry and be brushed off first. The American Cleaning Institute's advice for grass is to pretreat or soak in a product containing enzymes, then wash. Mississippi State's guide adds a wash in the hottest water the fabric can take, with a bleach that is safe for it.

Mud is the one stain to leave alone for a while. Wiping wet mud pushes it into the weave. The cleaning institute says to let it dry and brush off as much as possible, and Texas A&M AgriLife's quick guide suggests a soak of at least 30 minutes in detergent and water before washing. On cream or white cotton pants, do the brushing outside: the dry dust goes everywhere.

Food stains: tomato, berries, chocolate and milk

Rinse cold from the back, pretreat, then wash. Only the water temperature changes from food to food.

  • Tomato sauce and ketchup. The cleaning institute says to run cold water through the back of the stain, not the front, so it doesn't spread. Mississippi State suggests a soak in cool water with detergent afterwards.
  • Berries and juice. These are tannin stains. The University of Kentucky says fresh tannin stains usually wash out with detergent and hot water. If a mark is left, the cleaning institute suggests a bleach that is safe for the fabric.
  • Chocolate. Scrape off the excess gently, soak in cool water, pretreat and wash, according to the cleaning institute.
  • Milk, yogurt, egg and formula. Protein stains: cold water, then an enzyme pretreatment or soak. Mississippi State suggests at least 30 minutes for formula.

Pale cotton shows food more than a print does. The Bellagio shirt is pale yellow, and the method above is the same for it as for a white tee.

Potty accidents and vomit

Rinse in cold water as soon as you can, then use an enzyme pretreatment and wash. The American Cleaning Institute groups these as bodily fluids and gives the same answer: pretreat or soak in a product containing enzymes. Mississippi State's guide covers vomit, urine and feces together, with enzymes first and then a bleach that is safe for the fabric if a mark remains.

If any stain remover you use contains ammonia, never use chlorine bleach in the same wash or the same basin: Health Canada warns that bleach reacts with products containing ammonia or acids, including vinegar, and gives off toxic gases. For a toilet-training child, a basin of cold water and an enzyme product by the laundry tub is the simpler routine. Our guide to why kids' clothes still smell after washing covers what to do when a smell stays after the stain has gone.

Crayon, gum, paint and pen

Harden wax and gum, catch paint while it is wet, and test before you fight ink.

  • Crayon. Scrape off what you can. The University of Georgia's guide says to put the stain face down on a pad of white paper towels and work in a pre-wash stain remover from the back. For a whole load that went through with a crayon in a pocket, the cleaning institute suggests a hot wash with laundry soap and a cup of baking soda. Keep the load out of the dryer until every mark is gone.
  • Gum. Texas A&M AgriLife says to harden it with ice, then crack or scrape it off. Mississippi State suggests a dull knife. Pretreat what is left and wash.
  • Water-based paint. The cleaning institute says to rinse in warm water while the paint is still wet, and that once paint is dry it cannot be removed. For paint labelled washable, follow the maker's own instructions too.
  • Pen and marker. The cleaning institute suggests sponging with rubbing alcohol. The University of Kentucky says some inks may be impossible to remove, and Mississippi State says felt-tip marker usually cannot be removed. Test on a seam first, and don't use alcohol near an open flame.
Health Canada

“Keep out of sight and out of reach of children and pets.”

Use household chemicals safely, Health Canada, 2026

Sunscreen stains: where the guides disagree

Blot it, massage in liquid detergent or dish soap, wash, then air dry and check. That is Iowa State University Extension's 2025 advice. It also warns against soaking a sunscreen stain and against chlorine or oxygen bleach, which it says may make the stain worse. Some older guides tell you to use bleach on the same stain. We would follow the newer, more cautious advice on a coloured piece, because bleach can't be undone.

Either way, air dry and check: a sunscreen mark that is still there after the wash should be treated again before the piece goes in the dryer.

When should you use bleach on kids' clothes?

Only when the stain is still there after washing, and only the kind of bleach the care label allows. New Mexico State University says chlorine bleach is best for white cotton and linen. On coloured, printed or embroidered cotton, an oxygen bleach is the usual choice, if the label allows any bleach at all.

The care label tells you which. Under the US Federal Trade Commission's care labelling rule, a label must say "only non-chlorine bleach, when needed" if chlorine bleach would harm the piece, and "no bleach" or "do not bleach" if any bleach would. In Canada, care labelling is voluntary, the Competition Bureau says, so not every piece has a label. When there is none, test on a hidden seam. Our guide to reading a kids' clothing label explains the care symbols.

Rust is the exception to the bleach rule: the cleaning institute says chlorine bleach can make rust stains worse, and Mississippi State says not to use it on rust.

Keeping stain removers safe around kids

Store them high and closed, and never mix them. Health Canada says to keep household chemicals out of sight and out of reach of children and pets, and warns that laundry detergent packets can be attractive to children. It also says never to mix bleach with other chemicals, including products that contain ammonia or acids such as vinegar. New Mexico State's guide gives the same two rules: keep stain removers locked up and out of children's reach, and don't mix them, especially ammonia and chlorine bleach.

A stain stick in the diaper bag or daycare bag is handy. Keep it in a zipped pocket the child can't open.

Which stains are permanent?

Dried paint, permanent marker, some inks, and any stain that has been through the dryer are the most likely to stay. The cleaning institute says dried paint can't be removed. The University of Kentucky and Mississippi State say the same of some inks and felt-tip markers. A stain that has been set by heat may lighten with repeated treatment, but none of the guides promises it will go.

A stain that won't come out doesn't have to end a piece. A pair of pants with grass on the knees is still a good pair of pants for the park, and a shirt with a faint mark still layers under a sweater. Before you put clothes away for a younger child, treat stains first: our guide to storing kids' clothes for the next child explains why old food residue can turn yellow in a bin. And our six tests for clothes that survive two kids help you decide what is worth keeping.

What we don't know

Several of the extension guides we used are decades old (Kentucky's and Texas A&M's date from the 1990s), and laundry products have changed since. Their methods still match the American Cleaning Institute's 2026 guide on the basics, but where newer advice differs, as with sunscreen, we have gone with the newer source. None of the guides tests organic cotton separately from conventional cotton, and we know of no reason the methods would differ. We have not tested these methods on our own clothes. Always follow the care label where there is one.

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Frequently asked questions

How do you get stains out of kids' clothes?
Scrape or blot off what you can, rinse the back of the stain with cold water, rub in liquid detergent or an enzyme stain remover, then wash. Air dry and check before using the dryer, because dryer heat can set a stain that is still there.
Should I use hot or cold water on stains?
Start with cold water for protein stains such as milk, egg, blood, vomit and potty accidents, because hot water can set them. Once the stain is gone, or for grass, berries and grease, wash in the warmest water the care label allows.
What gets grass stains out of kids' pants?
An enzyme stain remover worked into the stain, left for a while, then a wash in the warmest water the care label allows. The American Cleaning Institute recommends a product containing enzymes for grass.
How do you get crayon out of clothes?
Scrape off what you can, put the stain face down on white paper towels and work in a pre-wash stain remover from the back, then wash. Keep it out of the dryer, because heat melts wax into the fabric.
How do you get sunscreen stains out of clothes?
Blot the stain, massage in liquid detergent or dish soap, wash, then air dry and check. Iowa State University Extension warns against soaking and against chlorine or oxygen bleach, which it says may make the stain worse.
Can I use bleach on kids' clothes?
Chlorine bleach is best kept for white cotton, and only if the care label allows it. On coloured or embroidered pieces, use an oxygen bleach if the label allows any bleach, and test it on a hidden seam first. Never mix bleach with ammonia or vinegar.
Do stains come out after going through the dryer?
Sometimes they lighten with repeated treatment, but dryer heat can set a stain for good. The American Cleaning Institute and Texas A&M AgriLife both say to keep a stained piece out of the dryer until the stain is gone.
Which stains are permanent?
Dried paint, permanent marker, some inks and stains set by dryer heat are the most likely to stay. Treat paint while it is wet, and test rubbing alcohol on a hidden spot before working on ink.

Clothes made to be handed down

Shirts, pants, shorts and blouses in 100% combed organic cotton for ages 2 to 6, made by GOTS-certified manufacturers and designed in Canada to be handed down. Free shipping across Canada and the US, and 60-day returns.

Shop the collection

Topics:
caring for clothes cotton how-to guide laundry stains

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